- His experiment involved mice and 2 types of pneumonia ( a virulent kind & a non-virulent kind)
- the virulent pneumonia injection + mouse= it ended up dying.
- the non-virulent pneumonia injection+ mouse= ended up living
- He then heated up the virulent disease & killed it , then injected it into another mouse, it ended up living.
- Lastly he heated up the virulent & non-virulent pneumonia, then injected it into another mouse, it ended up dying.
- Griffith discovered the passing on of the inheritance molecule was what he called "transformation".
James Watson & Francis Crick
- Watson and Crick used a picture of crystallized DNA to put together a model of DNA.
- They found out that if you paired Thymine with Adenine and Guanine with Cytosine, the DNA would be uniformed.
- Their model showed a double helix with bases of nucleotide connecting the 2 strands.
Oswald Avery
- Avery followed up on Griffith's experiment.
- He destroyed the lipids, ribonucleic acids, carbohydrates, & proteines of the virulent pneumonia. Resulting in transformation
- He then destoryed the DNA, and transformation did not occur.
- Avery discovered the inheritance molecule (DNA).
Questions
1. Name another experiment dealing with DNA and what did they discover?
2. What is transformation?
3. Who also contributed to the discovery of the model of DNA?
1. Another prominent figure in DNA experimenting was Maclyn McCarty. McCarty along with Oswald Avery and Colin Munro Mac Leod performed many experiements to prove DNA was a substance which controlled heredity in living cells.
ReplyDelete2. The uptake and expression of foreign DNA in a living cell. Originally defined as an inherited alteration of the phenotype of the transformed cell
3. Rosalind Franklin had discovered the DNA Model in earlier experiments and along with a lab partner wrote 5 essays on their finds. The papers were later used by Watson and Crick for the foundation of their experiments.
1.Alfred Hershey and Martha Chase discovered DNA was the basic building block of genetics, not protein.
ReplyDelete2.The genetic altering of a cell by transferring genetic material to another cell.
3.Erwin Chargaff discovered two rules which helped lead to the discovery of the double helix model. His rules basically state that DNA from any cell in all organisms should have a 1:1 ratio of Guanine to Cytosine and Adenine to Thymine
1.Girffith. he actually studyied an outbreak of pnuemonia. The logical conclusion then was that the transforming principle (or genetic material) was DNA. Also, the purified transforming principle exhibited all the chemical properties of DNA.
ReplyDelete2.Is the transfer of genetic material from one bacterium to another through the liquid in which bacteria live.
3.Maurice Wilkins also helped discover DNA.